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Nanomaterial surface modification toolkit: Principles, components, recipes, and applications.
Sümeyra Vural Kaymaz1, Hediyeh Malekzadsani Nobar2, Hasan Sarıgül2
1Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul 34956, Turkey; SUNUM Nanotechnology Research and Application Centre, Sabanci University, Istanbul 34956, Turkey.
Advances in Colloid and Interface Science
|November 6, 2023
Summary
Surface functionalization of nanostructures enhances biotechnology applications like biosensors and drug delivery. This review details modification strategies and their impact on nano-bio interfaces for diverse applications.
Area of Science:
- Biotechnology and Nanotechnology Interface
- Materials Science and Surface Chemistry
Background:
- Surface-functionalized nanostructures are crucial for advanced biotechnology.
- Nanostructure modification enables precise targeting and improves application performance.
Purpose of the Study:
- To review widely practiced surface modification strategies for nanostructures.
- To explore the application landscape of the nano-bio interface in key domains.
- To provide a comprehensive overview for researchers in nanotechnology and biotechnology.
Main Methods:
- Elucidation of various surface modification techniques: click chemistry, cross-coupling, silanization, etc.
- Analysis of protein and DNA-based methodologies for nanostructure functionalization.
- Review of recent literature (2018-2023) on nano-bio interface applications.
Main Results:
- Detailed overview of diverse chemical strategies for nanostructure surface functionalization.
- Highlighting prominent studies in therapeutics, biosensing, environmental monitoring, and point-of-care technologies.
- Demonstration of how surface modification impacts nano-bio interface applications.
Conclusions:
- Surface modification is key to unlocking the potential of nanostructures in biotechnology.
- The review serves as a handbook for innovations in nanotechnology and biotechnology.
- Future research directions are suggested for the nano-bio interface.
