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Updated: Jul 11, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
A Case of Lip Psoriasis in a 14-Year-Old Boy Successfully Treated with Adalimumab
Francesca Caroppo1, Laura Gnesotto1, Maria Ludovica Deotto1
1Department of Medicine DIMED & Department of Women's and Children's Health SDB, Pediatric Dermatology Regional Center, University of Padova, Padova, Italy.
Abstract:
Psoriasis is a common chronic skin disease mainly located in areas of friction. Psoriasis of the lips as an exclusive presentation is rare and often misdiagnosed. Different anti-psoriatic therapies have been proposed, but the literature is limited to case studies with partial results. Biologic therapies have revolutionized the management of many dermatologic conditions, including psoriasis, and they are approved for pediatric use. We report the case of a 14-year-old boy with a 2-year history of white-yellowish scaling lesions on his lips, without intraoral involvement. Lip biopsy showed a psoriasiform pattern. Treatment with adalimumab 40 mg every other week was started, and after 6 months of therapy, we obtained a complete remission of the patient's lip psoriasis.

