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Updated: Jul 11, 2025

Author Spotlight: Enhancing Rheumatoid Arthritis Research Through HR-pQCT Imaging Analysis
Published on: October 6, 2023
EXPLORing Arthritis with Total-body Positron Emission Tomography
Abhijit J Chaudhari1, Yasser G Abdelhafez1,2, Lorenzo Nardo1
1Department of Radiology, University of California, Davis, Davis, California.
Total-body positron emission tomography (PET) offers a new way to monitor arthritis. This advanced imaging technique may help find new biomarkers for assessing arthritis activity and its systemic effects.
Area of Science:
- Medical Imaging
- Rheumatology
- Biomarkers
Background:
- Arthritis significantly impacts musculoskeletal tissues and other organs.
- Current clinical evaluation methods for arthritis are suboptimal.
- Objective biomarkers for monitoring arthritis disease activity are critically needed.
Approach:
- Total-body positron emission tomography (PET) systems have been developed for whole-body imaging.
- These scanners operate at ultra-low radiation doses and reduced scan times.
- Increased signal collection efficiency addresses limitations of standard PET scanners.
Key Points:
- Total-body PET can assess the local and systemic impact of arthritis.
- It shows potential for developing novel imaging biomarkers for arthritis.
- This technology overcomes limitations of conventional PET in arthritis evaluation.
Conclusions:
- Total-body PET presents a promising advancement for arthritis assessment.
- Further research can explore its full potential in diagnosing and monitoring arthritis.
- Challenges and opportunities exist in integrating this technology into clinical practice.
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