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COVID-19 Outcomes in Inflammatory Bowel Disease Hospitalized Patients: A Comprehensive Analysis Using the National
Justin M Joseph1, Anum Akhlaq2, Rehmat Ullah Awan3
1Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.
Gastroenterology Research
|November 8, 2023
Summary
People with inflammatory bowel disease (IBD) hospitalized with coronavirus disease 2019 (COVID-19) did not face worse outcomes. Our study found no significant differences in mortality, hospital stay length, or costs for COVID-19 patients with IBD.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Public Health
Background:
- Literature lacks consensus on coronavirus disease 2019 (COVID-19) effects in inflammatory bowel disease (IBD) patients.
- Inflammatory bowel disease (IBD) encompasses chronic gastrointestinal conditions.
- COVID-19 is a significant global health concern.
Purpose of the Study:
- To investigate the impact of COVID-19 on hospitalized patients with and without inflammatory bowel disease (IBD).
- To compare mortality rates, length of hospital stay, and hospitalization costs between COVID-19 patients with and without IBD.
Main Methods:
- Analysis of the 2020 National Inpatient Sample (NIS) database.
- Comparison of outcomes for 1,050,040 COVID-19 admitted patients, including 5,750 with IBD.
- Statistical adjustment for confounding variables.
Main Results:
- Patients with COVID-19 and IBD showed higher prevalence of females, White individuals, and comorbidities like chronic lung, peripheral vascular, and liver diseases.
- No significant differences in mortality rates were observed between groups.
- Length of hospital stay and hospitalization costs were comparable between COVID-19 patients with and without IBD after adjustments.
Conclusions:
- The presence of inflammatory bowel disease (IBD) does not appear to increase the risk of severe COVID-19 complications.
- Hospitalized COVID-19 patients with IBD experienced similar outcomes to those without IBD.
- Findings suggest IBD is not a significant risk factor for adverse COVID-19 outcomes.
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