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Updated: Jul 11, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
How standardised are antibiotic regimens in otologic surgery?
Justin T Lui1,2, Valerie Dahm3,4, Christoph Arnoldner5
1Section of Otolaryngology-Head and Neck Surgery, Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Surgeons show inconsistent antibiotic prescribing for otologic surgery, particularly for stapes and tympanoplasty procedures. This highlights a lack of consensus and challenges adherence to clinical practice guidelines for preventing surgical site infections.
Area of Science:
- Otolaryngology
- Surgical Infections
- Antibiotic Stewardship
Background:
- Limited studies exist on systemic antibiotic use to prevent surgical site infections in otologic surgery.
- Discrepancies in wound classification complicate antimicrobial prescribing guidelines.
Purpose of the Study:
- To compare antibiotic prescribing habits of otologic surgeons in Canada and Austria.
- To assess adherence to practice guidelines for various otologic procedures.
Main Methods:
- An online questionnaire surveyed 33 Canadian and 32 Austrian otologic surgeons.
- Prescribing habits for cochlear implantation, cholesteatoma surgery, stapes surgery, and tympanoplasty were collected.
Main Results:
- Consistent guideline adherence for pre-operative antibiotics in cochlear implant and infected cholesteatoma surgery.
- Lack of consensus for stapes surgery and tympanoplasty regarding pre- and post-operative antibiotics.
- Significant international differences in post-operative antibiotic use for cochlear implant and uninfected cholesteatoma surgery.
Conclusions:
- Lack of consensus among otologic surgeons indicates uncertainty in wound classification.
- This uncertainty impacts adherence to established clinical practice guidelines for antibiotic use.
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