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Updated: Jul 11, 2025

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Retained Gastric Contents After Adequate Fasting Associated with GLP-1 Receptor Agonist Use: A Report of 3 Cases
Sarah L Kittner1, Ashley L Talbott1, Susan R Vishneski1
1Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Cases:
Three patients presented for orthopaedic surgery on glucagon-like peptide receptor agonist (GLP-1 RA) medications with a minimum fasting time of 10 hours. Gastric ultrasound confirmed the presence of retained solids in the stomach; all 3 cases were postponed.
Conclusion:
There is growing concern for increased perioperative aspiration risk related to delayed gastric emptying associated with GLP-1 RA and a paucity of literature to guide perioperative management. This may cause case cancellation over safety concerns for elective procedures. The presented cases illustrate the association of GLP-1 RA drugs and delayed gastric emptying causing case postponement.
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