Altered Functional Connectivity in Working Memory Network After Acute Sleep Deprivation
Sitong Feng1, Hao Yao2, Sisi Zheng1
1The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China; Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China.
Neuroscience
|November 9, 2023
Summary
Acute sleep deprivation impairs working memory (WM) by altering brain connectivity. Findings reveal specific brain regions show abnormal activation and functional connectivity changes after sleep loss, impacting WM performance.
Area of Science:
- Neuroscience
- Cognitive Psychology
Background:
- Acute sleep deprivation (SD) negatively impacts working memory (WM).
- Previous functional magnetic resonance imaging (fMRI) studies show inconsistent results regarding brain function changes after SD.
- Convergent patterns of abnormal brain function related to WM decline after SD require identification.
Conclusions:
- Altered functional connectivity within the working memory network is a potential mechanism underlying WM decline after acute sleep deprivation.
- The study identifies specific brain regions and connectivity patterns affected by SD.
- Findings contribute to understanding the neurobiological basis of cognitive deficits following sleep loss.
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