Correlation between right-to-left shunt and sudden sensorineural hearing loss: protocol for a case-control study.

Area of Science:

• Neurology
• Otolaryngology
• Cardiology

Background:

• Sudden sensorineural hearing loss (SSNHL) is a critical neurological and otolaryngological emergency.
• Clinical observations suggest a frequent co-occurrence of SSNHL and right-to-left shunts (RLS).
• The relationship between SSNHL and RLS requires further investigation through large-scale studies.

Purpose of the Study:

• To explore the potential correlation between right-to-left shunts (RLS) and sudden sensorineural hearing loss (SSNHL).
• To investigate the prevalence of RLS in patients diagnosed with SSNHL.
• To contribute to a better understanding of the underlying causes of SSNHL.

Main Methods:

• A prospective, observational case-control study design.
• 194 participants (97 SSNHL cases, 97 controls) matched for age and sex.
• Data collection includes medical history, laboratory tests, audiological assessments, and ultrasonography.

Main Results:

• The primary outcome is the difference in RLS rates between SSNHL patients and controls.
• Patent foramen ovale rates and other variables will be analyzed.
• Conditional logistic regression will assess the relationship between RLS and SSNHL.

Conclusions:

• This study aims to provide evidence for the association between RLS and SSNHL.
• Findings may enhance the etiological understanding of SSNHL.
• Results will be disseminated through peer-reviewed publications.
• Meta_A_description:
• Meta_Description: "Investigate the link between sudden sensorineural hearing loss (SSNHL) and right-to-left shunts (RLS) in a case-control study exploring hearing loss etiology."
• TL_DR
• Sudden sensorineural hearing loss (SSNHL) is a neurological emergency. This study investigates the potential link between SSNHL and right-to-left shunts (RLS) to better understand hearing loss causes.
• Enhanced_Abstract
• Area_of_Science
• Neurology, Otolaryngology, Cardiology
• Background
• Sudden sensorineural hearing loss (SSNHL) is a critical neurological and otolaryngological emergency.
• Clinical observations suggest a frequent co-occurrence of SSNHL and right-to-left shunts (RLS).
• The relationship between SSNHL and RLS requires further investigation through large-scale studies.
• Purpose_of_the_Study
• To explore the potential correlation between right-to-left shunts (RLS) and sudden sensorineural hearing loss (SSNHL).
• To investigate the prevalence of RLS in patients diagnosed with SSNHL.
• To contribute to a better understanding of the underlying causes of SSNHL.
• Main_Methods
• A prospective, observational case-control study design.
• 194 participants (97 SSNHL cases, 97 controls) matched for age and sex.
• Data collection includes medical history, laboratory tests, audiological assessments, and ultrasonography.
• Main_Results
• The primary outcome is the difference in RLS rates between SSNHL patients and controls.
• Patent foramen ovale rates and other variables will be analyzed.
• Conditional logistic regression will assess the relationship between RLS and SSNHL.
• Conclusions
• This study aims to provide evidence for the association between RLS and SSNHL.
• Findings may enhance the etiological understanding of SSNHL.
• Results will be disseminated through peer-reviewed publications.