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Quantitative Evaluation of Hemodynamic Changes After Multiple Intracranial Aneurysms Occlusion Using Computational
Xu Yi1, Shuhua Zhang1, Qicheng Han1
1School of Mechanical Engineering and Automation, Fuzhou University, Fuzhou, China.
World Neurosurgery
|November 10, 2023
Summary
Treating middle cerebral artery (MCA) aneurysms first may be optimal for multiple intracranial aneurysms (MIA) when treatment order is unclear. Occluding ICA aneurysms significantly impacts MCA and ACA pressure, while MCA aneurysm occlusion has minimal effect on ICA and ACA hemodynamics.
Area of Science:
- Neurosurgery
- Medical Imaging
- Computational Fluid Dynamics
Background:
- Multiple intracranial aneurysms (MIA) present complex treatment challenges.
- Understanding hemodynamic effects of aneurysm treatment is crucial for patient outcomes.
Purpose of the Study:
- To analyze the hemodynamic impact of internal carotid artery (ICA) and middle cerebral artery (MCA) aneurysm occlusion in MIA.
- To determine optimal treatment order for MIA involving ICA and MCA aneurysms.
Main Methods:
- Utilized a 1D/3D computational fluid dynamics (CFD) model for 9 MIA patients.
- Simulated vascular flow patterns and wall pressure changes after aneurysm occlusion.
Main Results:
- ICA aneurysm occlusion increased MCA and anterior cerebral artery (ACA) pressure.
- MCA aneurysm occlusion minimally affected ICA and ACA pressure.
- Aneurysm size at MCA had negligible impact on ICA/ACA pressure; ICA aneurysm size influenced MCA/ACA pressure.
Conclusions:
- Prioritize MCA aneurysm treatment if patient/aneurysm factors don't dictate order.
- Hemodynamic analysis guides strategic intervention for MIA.
