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Updated: Jul 11, 2025

Genome Editing in Mammalian Cell Lines using CRISPR-Cas
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Genome Editing in Mammalian Cell Lines using CRISPR-Cas

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Type III CRISPR-Cas: beyond the Cas10 effector complex

Gianna Stella1, Luciano Marraffini2

  • 1Laboratory of Bacteriology, The Rockefeller University, New York, NY 10065, USA; Tri-Institutional PhD Program in Chemical Biology, Weill Cornell Medical College, Rockefeller University and Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Trends in Biochemical Sciences
|November 10, 2023
PubMed

Keywords:
CARF-domain effectorsCRISPR immunityCas7-11ancillary nucleasescyclic oligoadenylates (cOA)ring nucleasesBacteriophage defenseCARF-domain effectorsCraspase complexCyclic oligoadenylatesRing nucleases

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