Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Blood-induced arterial segmental spasm.

S M Hou, A V Seaber, J R Urbaniak

    Journal of Reconstructive Microsurgery
    |October 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [The consistency of skeletal muscle mass measured by CT at L<sub>1</sub> and L<sub>3</sub> levels and the correlation of skeletal muscle density at L<sub>1</sub> level with prognosis in dialysis patients].

    Zhonghua yi xue za zhi·2023
    Same author

    Adaptation and external validation of the European randomised study of screening for prostate cancer risk calculator for the Chinese population.

    Prostate cancer and prostatic diseases·2016
    Same author

    Current management practice for bladder cancer in Hong Kong: a hospital-based cross-sectional survey.

    Hong Kong medical journal = Xianggang yi xue za zhi·2014
    Same author

    Age, tumour stage, and preoperative serum albumin level are independent predictors of mortality after radical cystectomy for treatment of bladder cancer in Hong Kong Chinese.

    Hong Kong medical journal = Xianggang yi xue za zhi·2013
    Same author

    Reliability and validity of the overactive bladder symptom score in Hong Kong Chinese.

    Hong Kong medical journal = Xianggang yi xue za zhi·2013
    Same author

    The innervation of canine hip joint capsule: an anatomic study.

    Anatomia, histologia, embryologia·2013

    Blood from side branches can cause dangerous arterial spasm, threatening replant survival. Careful ligation of these branches is crucial to prevent this vasospasm and ensure tissue viability.

    Area of Science:

    • Vascular Surgery
    • Surgical Complications
    • Tissue Engineering

    Background:

    • Blood-induced arterial segmental spasm is a recognized clinical issue.
    • It is hypothesized to occur when extravasating blood contacts a main feeding artery.
    • This spasm can jeopardize the success of replantation or flap transfer procedures.

    Purpose of the Study:

    • To investigate the phenomenon of blood-induced arterial segmental spasm.
    • To determine the impact of side branch bleeding on main artery vasospasm and limb perfusion.
    • To evaluate the efficacy of heparin, aspirin, and endothelial protection in mitigating this spasm.

    Main Methods:

    • A partially amputated rat hind limb model was utilized.
    • Bleeding from a side branch was induced and its effect on the main artery observed.

    Related Experiment Videos

  • Vascular spasm and limb perfusion were assessed, with varying pretreatments (heparin, aspirin, endothelial protection).

    • Main Results:

    • Direct contact between extravasated blood from a side branch and the main artery caused severe vasoconstriction and reduced limb perfusion.
    • Pretreatment with heparin and minimization of endothelial damage significantly decreased vasospasm.
    • Aspirin pretreatment did not affect the degree of vasospasm or reduced blood flow.

    Conclusions:

    • Careful ligation of arterial side branches is clinically important to prevent vasospasm.
    • Preventing direct contact between bleeding side branches and main arteries is essential for successful replantation and flap survival.
    • Understanding the mechanisms of vasospasm aids in developing strategies to improve surgical outcomes.