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Recurrence of Rathke's Cleft Cyst Following Surgery and Histopathological Considerations for Recurrence: A Case
Dongwook Lee1, Jang Hun Kim1, Dong-Hyuk Park1
1Department of Neurosurgery, Anam Hospital, Korea University Medical Center, Korea University College of Medicine, Seoul, Korea.
Abstract:
Recurrence of Rathke's cleft cysts (RCC) following surgery is not uncommon. We present a 33-year-old male patient with chronic headache and visual disturbances whose MRI showed mostly cystic, suprasellar mass with peripheral enhancement. Endoscopic extended transsphenoidal approach and tumor resection was performed and RCC was pathologically confirmed postoperatively. Early recurrence was first suspected at 3 months following surgery, and his serial MRIs showed a recurred mass without associated clinical symptoms. Upon further histopathological study, extensive squamous metaplasia and high Ki-67 were seen. Also, in this study, we discuss important factors associated with cyst recurrence following surgery.
Insights
Rathke's cleft cyst recurrence after surgery is common. This case highlights factors like squamous metaplasia and high Ki-67, important for understanding and managing cyst regrowth.
Area of Science:
- Neurosurgery
- Endocrinology
- Pathology
Background:
- Rathke's cleft cysts (RCC) can recur after surgical resection.
- Chronic headache and visual disturbances are common symptoms.
