Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

1.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.3K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.5K
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

2.6K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
2.6K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.8K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

217
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
217

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Harnessing invasive plant species into valuable products.

Frontiers in plant science·2026
Same author

Genomic analysis highlights a novel class of DPCF-type cyanobacteriochrome.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2026
Same author

Tracing the origins of crmA megasynthase through lichen genomes.

Current biology : CB·2026
Same author

Mental Health Disorders in End-Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management.

Hemodialysis international. International Symposium on Home Hemodialysis·2026
Same author

Exploring the effects of high fat, salt, and sugar (HFSS) food consumption among undergraduate medical students: A cross-sectional study.

Journal of family medicine and primary care·2026
Same author

Investigation of Bioinspired Nanocurcumin Composites for Antibacterial Applications.

Critical reviews in therapeutic drug carrier systems·2026

Related Experiment Video

Updated: Jul 11, 2025

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
08:47

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer

Published on: April 21, 2022

3.4K

Muco-Obstructive Lung Disease: A Systematic Review.

Garima Singh1, Sourya Acharya1, Samarth Shukla2

  • 1Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Cureus
|November 13, 2023
PubMed
Summary

Muco-obstructive lung diseases involve thick mucus buildup in the airways, leading to conditions like COPD and cystic fibrosis. Understanding this classification is key to managing chronic respiratory issues.

Keywords:
copdcystic fibrosisinfectionmuco ciliary clearancemucusnon-cystic fibrosis bronchiectasisobstructive lung diseaseprimary ciliary dyskinesiarespiratory tract

More Related Videos

Author Spotlight: An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension
05:19

Author Spotlight: An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension

Published on: September 1, 2023

1.5K
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

20.5K

Related Experiment Videos

Last Updated: Jul 11, 2025

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer
08:47

Rapid Viscoelastic Characterization of Airway Mucus Using a Benchtop Rheometer

Published on: April 21, 2022

3.4K
Author Spotlight: An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension
05:19

Author Spotlight: An Effective Traditional Chinese Medicinal Treatment for Chronic Obstructive Pulmonary Disease with Abdominal Distension

Published on: September 1, 2023

1.5K
Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
10:01

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

20.5K

Area of Science:

  • Pulmonology and Respiratory Medicine
  • Pathophysiology of Lung Diseases

Background:

  • Muco-obstructive lung disease is a newly proposed classification for respiratory diseases.
  • Characterized by impaired mucus clearance due to thick mucin, heavy mucus, or ciliary dysfunction.
  • Leads to mucus accumulation in alveoli and distal airways, causing inflammation and infection.

Purpose of the Study:

  • To define muco-obstructive lung disease and differentiate it from other respiratory conditions.
  • To explore the impact of these diseases on respiratory system physiology.
  • To provide an overview of included conditions: COPD, CF, PCD, and NCFB.

Main Methods:

  • Review of existing literature and classifications of respiratory diseases.
  • Analysis of the pathophysiology of mucus accumulation and its consequences.
  • Comparative discussion contrasting muco-obstructive diseases with obstructive and restrictive lung diseases.

Main Results:

  • Muco-obstructive lung diseases are characterized by airway obstruction from accumulated mucus.
  • Key symptoms include chronic cough, sputum production, and acute exacerbations.
  • Conditions like COPD, CF, PCD, and NCFB fall under this classification, distinct from asthma.

Conclusions:

  • Muco-obstructive lung disease represents a significant category of respiratory illness impacting lung function.
  • Further understanding is needed to elucidate its distinct physiological effects and management strategies.
  • This classification aids in recognizing and addressing specific challenges posed by mucus obstruction.