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Updated: Jul 11, 2025

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Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
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Thyroid Metastasis to the Colon.
Eliza B Lewine1, Zinal Patel1, Jacqueline Forman1
1Department of Gastroenterology, New York University Langone Hospital Long Island, Mineola, NY.
ACG Case Reports Journal
|November 13, 2023
Summary
Metastatic colon cancer from a thyroid primary is rare. This case highlights the importance of colorectal cancer screening after thyroid cancer diagnosis and regular follow-up screening.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Colorectal cancers (CRC) are rarely caused by metastasis from other primary sites, with common origins including lung, breast, and prostate.
- Metastasis to the colon from a thyroid primary neoplasm is exceptionally uncommon.
Observation:
- A 76-year-old male patient with a history of papillary thyroid carcinoma presented with colon polyps.
- Colonoscopic and histopathological examination revealed polyps consistent with metastatic carcinoma originating from his primary thyroid cancer.
Findings:
- The patient's colon polyps were histologically confirmed as metastatic papillary thyroid carcinoma.
- This case represents an exceedingly rare instance of thyroid cancer metastasizing to the colon.
Implications:
- The findings suggest that patients with a history of thyroid cancer should undergo prompt and regular colorectal cancer screening.
- Early detection through screening may improve outcomes for patients with rare metastatic presentations of thyroid cancer.
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