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Polymer Microarrays for High Throughput Discovery of Biomaterials
Published on: January 25, 2012
Recent Advances in Molecularly Imprinted Polymers and Their Disease-Related Applications
Celia Cabaleiro-Lago1, Sylwia Hasterok2,3, Anette Gjörloff Wingren1,2,3
1Department of Bioanalysis, Faculty of Natural Sciences, Kristianstad University, 291 39 Kristianstad, Sweden.
Abstract:
Molecularly imprinted polymers (MIPs) and the imprinting technique provide polymeric material with recognition elements similar to natural antibodies. The template of choice (i.e., the antigen) can be almost any type of smaller or larger molecule, protein, or even tissue. There are various formats of MIPs developed for different medical purposes, such as targeting, imaging, assay diagnostics, and biomarker detection. Biologically applied MIPs are widely used and currently developed for medical applications, and targeting the antigen with MIPs can also help in personalized medicine. The synthetic recognition sites of the MIPs can be tailor-made to function as analytics, diagnostics, and drug delivery systems. This review will cover the promising clinical applications of different MIP systems recently developed for disease diagnosis and treatment.

