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YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution

J Silvio Gutkind1, Farhoud Faraji2, Sydney Ramirez3

  • 1University of California, San Diego.

Research Square
|November 14, 2023
PubMed
Summary

This study reveals how normal cells become cancer stem cells (CSCs) in living organisms. These CSCs recruit other cells to invade tissues, offering new targets for early cancer detection and prevention.

Keywords:
Cancer stem cellHNSCCHPVHippo pathwayOral cancerSquamous cell carcinomaTumor initiating cellTumor initiationYAP

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