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Cervical Cancer Classification From Pap Smear Images Using Deep Convolutional Neural Network Models.

Sher Lyn Tan1, Ganeshsree Selvachandran2,3, Weiping Ding4

  • 1Institute of Actuarial Science and Data Analytics, UCSI University, Jalan Menara Gading, Cheras, 56000, Kuala Lumpur, Malaysia.

Interdisciplinary Sciences, Computational Life Sciences
|November 14, 2023
PubMed
Summary
This summary is machine-generated.

This study introduces deep learning models for automated cervical cancer detection using Pap smear images. DenseNet-201 achieved the best performance, offering an efficient method for early cancer identification.

Keywords:
Cervical cancer classificationCervical cancer detectionConvolutional neural networkDeep learningMedical image processingPap smear images

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Area of Science:

  • Oncology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Cervical cancer is a common female malignancy with a prolonged pre-cancerous stage.
  • Traditional detection methods require complex cell segmentation and feature extraction.
  • Deep learning models (CNNs) often need large datasets, posing challenges for rare disease detection.

Purpose of the Study:

  • To develop deep learning models for automated cervical cancer detection without segmentation or custom features.
  • To leverage transfer learning with pre-trained CNNs for Pap smear image analysis.
  • To evaluate and compare the performance of 13 pre-trained deep CNN models.

Main Methods:

  • Utilized transfer learning with 13 pre-trained deep convolutional neural network (CNN) models.
  • Applied models directly to Pap smear images for a seven-class classification task.
  • Employed the publicly available Herlev dataset and the Keras package in Google Collaboratory.

Main Results:

  • DenseNet-201 demonstrated superior accuracy and performance among the evaluated models.
  • Pre-trained CNN models yielded promising experimental results.
  • The models required minimal computational time for analysis.

Conclusions:

  • Deep learning, particularly DenseNet-201, offers an effective approach for automated cervical cancer detection from Pap smear images.
  • Transfer learning mitigates data limitations, enabling robust classification.
  • This method provides an efficient and accurate tool for early cervical cancer screening.