Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FORCETRACKER: A versatile tool for standardized assessment of tissue contractile properties in 3D Heart-on-Chip platforms.

PloS one·2025
Same author

An organ-on-chip device with integrated charge sensors and recording microelectrodes.

Scientific reports·2023
Same author

Scalable large-area mesh-structured microfluidic gradient generator for drug testing applications.

Biomicrofluidics·2022
Same author

Rapid Prototyping of Organ-on-a-Chip Devices Using Maskless Photolithography.

Micromachines·2022
Same author

Three-dimensional self-assembly using dipolar interaction.

Science advances·2020
Same author

Statistical reprogramming of macroscopic self-assembly with dynamic boundaries.

Proceedings of the National Academy of Sciences of the United States of America·2020

Related Experiment Video

Updated: Jul 11, 2025

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance
10:51

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

16.3K

Integrated Electrochemical and Optical Biosensing in Organs-on-Chip.

Pratik Tawade1, Massimo Mastrangeli1

  • 1Electronic Components, Technology and Materials, Department of Microelectronics, Delft University of Technology, Mekelweg 4, 2628CD, Delft, Netherlands.

Chembiochem : a European Journal of Chemical Biology
|November 15, 2023
PubMed
Summary
This summary is machine-generated.

Integrated biosensing offers precise, real-time monitoring for organs-on-chip, advancing drug testing and personalized medicine through electrical, electrochemical, and optical methods.

Keywords:
biosensorsorgan-on-chipelectrochemical sensorsmicrophysiological systemsoptical sensors

More Related Videos

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

26.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K

Related Experiment Videos

Last Updated: Jul 11, 2025

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance
10:51

Fabrication and Validation of an Organ-on-chip System with Integrated Electrodes to Directly Quantify Transendothelial Electrical Resistance

Published on: September 26, 2017

16.3K
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
14:44

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips

Published on: October 20, 2018

26.7K
Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
13:42

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

11.8K

Area of Science:

  • Biomedical Engineering
  • Sensor Technology
  • Organ-on-Chip Technology

Background:

  • Growing demand for biocompatible, non-invasive, real-time monitoring in organs-on-chip.
  • Limitations of current sensors in achieving highest accuracy and sensitivity for in vitro microenvironment analysis.

Purpose of the Study:

  • To review integrated electrical, electrochemical, and optical sensing methods for organ-on-chip devices.
  • To highlight advancements and challenges in biosensing integration for organ-on-chip technology.

Main Methods:

  • Review of integrated electrical sensing methods.
  • Review of integrated electrochemical sensing methods.
  • Review of integrated optical sensing methods within organ-on-chip platforms.

Main Results:

  • Integrated biosensing enables in situ monitoring of microenvironment and dynamic tissue responses.
  • Precise detection of analytes and biochemical reactions enhances monitoring capabilities and reproducibility.
  • These methods deepen the understanding of organ functions.

Conclusions:

  • Integration of biosensing significantly advances organ-on-chip technology.
  • Paves the way for applications in drug testing, disease modeling, and personalized medicine.
  • Further research in biosensing integration is crucial for innovation.