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Updated: Jul 11, 2025

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Modelling inter-individual variability in acute and adaptive responses to interval training: insights into exercise
Arthur Henrique Bossi1,2,3, Ulrike Naumann4, Louis Passfield5
1School of Sport and Exercise Sciences, University of Kent, Canterbury, Kent, UK. a.bossi@napier.ac.uk.
Purpose:
To investigate the influence of exercise intensity normalisation on intra- and inter-individual acute and adaptive responses to an interval training programme.
Methods:
Nineteen cyclists were split in two groups differing (only) in how exercise intensity was normalised: 80% of the maximal work rate achieved in an incremental test (% max) vs. maximal sustainable work rate in a self-paced interval training session (% max-SP). Testing duplicates were conducted before and after an initial control phase, during the training intervention, and at the end, enabling the estimation of inter-individual variability in adaptive responses devoid of intra-individual variability.
Results:
Due to premature exhaustion, the median training completion rate was 88.8% for the % max group, but 100% for the % max-SP the group. Ratings of perceived exertion and heart rates were not sensitive to how intensity was normalised, manifesting similar inter-individual variability, although intra-individual variability was minimised for the % max-SP group. Amongst six adaptive response variables, there was evidence of individual response for only maximal oxygen uptake (standard deviation: 0.027 L·min-1·week-1) and self-paced interval training performance (standard deviation: 1.451 W·week-1). However, inter-individual variability magnitudes were similar between groups. Average adaptive responses were also similar between groups across all variables.
Conclusions:
To normalise completion rates of interval training, % max-SP should be used to prescribe relative intensity. However, the variability in adaptive responses to training may not reflect how exercise intensity is normalised, underlining the complexity of the exercise dose-adaptation relationship. True inter-individual variability in adaptive responses cannot always be identified when intra-individual variability is accounted for.
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