Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

36.4K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.4K
Next-generation Sequencing03:00

Next-generation Sequencing

89.0K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
89.0K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

23
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
23
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

5.8K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.8K
Sanger Sequencing01:57

Sanger Sequencing

754.6K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
754.6K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

7.1K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Moral Injury, Moral Identity, and "Dirty Hands" in War Fighting and Police Work.

The Journal of medicine and philosophy·2022
Same author

A principled approach to cross-sector genomic data access.

Bioethics·2021
Same author

The ethical application of biometric facial recognition technology.

AI & society·2021
Same author

Ethics, public health and technology responses to COVID-19.

Bioethics·2021
Same author

Addressing the challenges of artificial intelligence in medicine.

Internal medicine journal·2020
Same author

Whither the University? Universities of Technology and the Problem of Institutional Purpose.

Science and engineering ethics·2019
Same journal

Reconciling Subsistence Emissions and Prevention in Environmentally Sustainable Healthcare.

Journal of bioethical inquiry·2026
Same journal

Why the Social Gradient in Health-Related Behaviour is Unjust : An Unconditionalist Perspective.

Journal of bioethical inquiry·2026
Same journal

Mapping the Representation of Race and Other Health Disparities in U.S. Orthopaedic Journals : A Scoping Review.

Journal of bioethical inquiry·2026
Same journal

Safeguarding Physical and Mental Health Rights in African Conflict Regions: Ethical Responsibilities, Barriers, and Collaborative Efforts.

Journal of bioethical inquiry·2026
Same journal

Ibsen's An Enemy of the People and the Ethics of Public Health Disclosure.

Journal of bioethical inquiry·2026
Same journal

Is Unconsciousness the Intention? Physicians' Perspectives on Palliative Sedation Outside Specialized Palliative Care: A Qualitative Study.

Journal of bioethical inquiry·2026
See all related articles

Related Experiment Video

Updated: Jul 11, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

19.5K

The Evolution of Forensic Genomics: Regulating Massively Parallel Sequencing.

Marcus Smith1, Seumas Miller2

  • 1Charles Sturt University, 10 Brisbane Avenue, Canberra, ACT 2600, Australia. marcussmith@csu.edu.au.

Journal of Bioethical Inquiry
|November 15, 2023
PubMed
Summary
This summary is machine-generated.

Forensic genomics using massively parallel sequencing (MPS) aids law enforcement. While collective responsibility supports DNA submission, strict legal limits are crucial to protect individual rights and prevent government overreach.

Keywords:
Biogeographical ancestryCollective responsibilityDNA evidenceForensic genomicsJoint rightsMassively parallel sequencing

More Related Videos

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.8K
Rare Event Detection Using Error-corrected DNA and RNA Sequencing
10:36

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

12.1K

Related Experiment Videos

Last Updated: Jul 11, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
11:02

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing

Published on: October 18, 2013

19.5K
Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
09:34

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

33.8K
Rare Event Detection Using Error-corrected DNA and RNA Sequencing
10:36

Rare Event Detection Using Error-corrected DNA and RNA Sequencing

Published on: August 3, 2018

12.1K

Area of Science:

  • Forensic Genomics
  • Bioethics
  • Law Enforcement Technology

Background:

  • Massively parallel sequencing (MPS) offers advanced forensic analysis of DNA, revealing traits, ancestry, and medical information.
  • Current use of MPS by law enforcement raises ethical concerns regarding individual privacy and governmental power balance.

Purpose of the Study:

  • To analyze the ethical implications of using massively parallel sequencing in forensic investigations.
  • To explore the concepts of joint rights and collective moral responsibility in the context of genomic data.
  • To propose a framework for the responsible use of forensic genomics.

Main Methods:

  • Ethical analysis drawing on legal and philosophical concepts of rights and responsibilities.
  • Review of the capabilities and societal impact of massively parallel sequencing in forensic science.

Main Results:

  • Unregulated MPS use risks violating individual rights and shifting power dynamics.
  • A collective moral responsibility exists for DNA submission when necessary for justice and security.
  • Legislation is needed to govern MPS use, ensuring data relevance and destruction post-investigation.

Conclusions:

  • Forensic genomics offers significant benefits but requires robust legal and ethical safeguards.
  • Balancing societal security with individual rights is paramount in the application of MPS.
  • Clear legislation and accountability mechanisms are essential for the ethical deployment of forensic genomic technologies.