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Universal regularities in protein primary structure: preference in bonding and periodicity
Abstract:
Utilizing the whole protein data base as well as parts of it (groups and individual representatives), the universal character of the regularities in protein primary structure - preference in bonding (self-ordering) and periodicity - is shown by means of an improved procedure of checking statistical significance. In the vast majority of the cases there is a preference in bonding with the same or with very similar amino acid. Taken as a whole, both regularities show a universal character. The results obtained provide evidence in favour of the conception about the priority of proteins as information polymers.