Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Conduction System of the Heart01:19

Conduction System of the Heart

7.6K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
7.6K
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

4.9K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
4.9K
Pulse01:05

Pulse

839
The pulse is one of the most fundamental physiological indicators of the body's cardiovascular health. It is the rhythmic expansion and contraction of the arterial walls in response to the pressure generated by the heart's pumping action.
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
839
Dysrhythmias I: Introduction01:15

Dysrhythmias I: Introduction

13
Dysrhythmias refers to abnormalities in the heart's rhythm. They result from disruptions in the heart's electrical conduction system, which includes the sinoatrial(SA)node, atrioventricular(AV) node, the bundle of His, bundle branches, and Purkinje fibers.Definition and PathophysiologyDysrhythmias result from disorders of impulse formation, impulse conduction, or both. The heart contains specialized cells in the sinoatrial node, atrioventricular node, and the bundle of His and Purkinje fibers...
13
Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

10
Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
10
Cardiac Action Potential01:30

Cardiac Action Potential

1.5K
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intracardiac Electrograms During Left Bundle Branch Area Pacing Implantation.

JACC. Clinical electrophysiology·2026
Same author

Predictors of pacing-induced cardiomyopathy in patients undergoing AV nodal ablation: insights from a Delphi process and retrospective cohort study.

European heart journal open·2026
Same author

Bridging the gap: adapting heart failure guidelines for resource-limited settings: A European Journal of Heart Failure expert consensus document.

European journal of heart failure·2026
Same author

Conduction System Pacing With AV Node Ablation Versus Pulmonary Vein Isolation: Emerging Evidence.

JACC. Asia·2026
Same author

Optimal pace timing for left bundle branch area pacing with or without an additional LV lead: results from the CSPOT study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Safety and performance of a novel ICD lead for left bundle branch area pacing: Results from the ASCEND CSP trial.

Heart rhythm·2026

Related Experiment Video

Updated: Jul 11, 2025

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.0K

Conduction system pacing: overview, definitions, and nomenclature.

Marek Jastrzebski1, Gopi Dandamudi2, Haran Burri3

  • 1First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University, Medical College, Jakubowskiego 2, 30-688 Krakow, Poland.

European Heart Journal Supplements : Journal of the European Society of Cardiology
|November 16, 2023
PubMed
Summary
This summary is machine-generated.

Conduction system pacing offers a more physiologic alternative to traditional right ventricular pacing, potentially reducing heart failure risks. Further trials are needed to confirm its benefits for bradycardia and heart failure pacing.

Keywords:
Conduction system pacingFascicular pacingHis bundle pacingLeft bundle branch area pacingLeft ventricular septal pacingRight bundle branch pacing

More Related Videos

Translational Rabbit Model of Chronic Cardiac Pacing
06:14

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

2.6K
Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.2K

Related Experiment Videos

Last Updated: Jul 11, 2025

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts
09:52

Optocardiography and Electrophysiology Studies of Ex Vivo Langendorff-perfused Hearts

Published on: November 7, 2019

13.0K
Translational Rabbit Model of Chronic Cardiac Pacing
06:14

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

2.6K
Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats
05:12

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

Published on: February 14, 2022

3.2K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Right ventricular apical pacing is linked to adverse outcomes, including heart failure, increased mortality, and reduced quality of life.
  • Conduction system pacing is emerging as a promising alternative to conventional pacing methods.

Purpose of the Study:

  • To review the clinical outcomes of conduction system pacing in various settings.
  • To illustrate the anatomical targets and electrocardiographic findings associated with conduction system pacing.

Main Methods:

  • Review of clinical results from studies investigating conduction system pacing.
  • Illustration of anatomical pacing targets.
  • Definition of electrocardiographic correlates for different pacing sites.

Main Results:

  • Conduction system pacing, particularly from the His bundle and left bundle branch area, promotes physiologic ventricular activation.
  • It is being explored as an alternative for both bradycardia and heart failure pacing.

Conclusions:

  • Conduction system pacing shows potential as an alternative to right ventricular apical pacing and coronary sinus pacing.
  • Comparative clinical trials are essential to establish the definitive benefits and risks of conduction system pacing versus standard techniques.