Related Experiment Video
Updated: Jul 11, 2025

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Update in lung transplantation: anesthetic considerations
Ashley V Fritz1, Miguel T Teixeira2, Saumil J Patel3
1Division of Cardiovascular and Thoracic Anesthesiology, Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, FL, USA.
Lung transplantation (LTx) has advanced significantly, with over 70,000 procedures performed globally. Modern perioperative care and anesthetic strategies are improving long-term outcomes for lung transplant recipients.
Area of Science:
- Cardiology
- Pulmonology
- Transplant Surgery
Background:
- Lung transplantation (LTx) has evolved from early single-specialty efforts to a global multidisciplinary field.
- Over 70,000 lung transplants have been completed worldwide, with ongoing advancements in managing end-stage lung disease.
- The multidisciplinary nature of LTx necessitates integrated anesthetic considerations into evolving patient care strategies.
Purpose of the Study:
- To review emerging strategies in lung transplantation (LTx).
- To highlight advancements in donor pool expansion, perioperative support, and anesthetic techniques.
- To discuss the impact of these strategies on long-term patient outcomes.
Main Methods:
- Review of current literature on lung transplantation (LTx) advancements.
- Discussion of strategies including donor pool expansion, extracorporeal life support, and echocardiography.
- Analysis of anesthetic techniques aimed at mitigating primary graft dysfunction.
Main Results:
- Significant improvements in perioperative care are enhancing 21st-century LTx practices.
- Emerging strategies are addressing challenges in LTx, leading to better patient management.
- Anesthetic considerations are crucial for integrating new surgical, medical, and systems techniques.
Conclusions:
- Advancements in LTx, including donor pool expansion and improved perioperative support, are enhancing patient outcomes.
- Anesthetic techniques play a vital role in mitigating primary graft dysfunction and improving long-term results.
- The integration of anesthesiologists into the multidisciplinary LTx team is essential for optimal patient care.
Related Concept Videos
Inhalational Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia

