Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Nucleus01:32

The Nucleus

74.7K
The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles.
Arrangement of DNA within Nucleus
The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...
74.7K
Nuclear Fission02:50

Nuclear Fission

9.5K
Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large...
9.5K
Nuclear Power02:36

Nuclear Power

7.5K
Controlled nuclear fission reactions are used to generate electricity. Any nuclear reactor that produces power via the fission of uranium or plutonium by bombardment with neutrons has six components: nuclear fuel consisting of fissionable material, a nuclear moderator, a neutron source, control rods, reactor coolant, and a shield and containment system.
Nuclear Fuels
Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...
7.5K
Nuclear Fusion02:45

Nuclear Fusion

33.3K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.3K
Nuclear Transmutation03:20

Nuclear Transmutation

13.0K
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
13.0K
The Nucleus01:25

The Nucleus

6.3K
The nucleus is a membrane-bound organelle that acts as a control center in a eukaryotic cell. It contains chromosomal DNA, which controls gene expression and precisely regulates the production of proteins within the cell. In contrast, the DNA inside the mitochondria and chloroplast only carries out functions that are specific to those organelles.
Arrangement of DNA within Nucleus
The regulation of gene expression inside the nucleus is dependent on many factors, including the DNA structure. The...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genome-wide chromatin recording resolves dynamic cell state changes.

bioRxiv : the preprint server for biology·2026
Same author

Synaptic MEMOIR: mapping individual synapses of neurons with protein barcodes.

bioRxiv : the preprint server for biology·2025
Same author

FAIR sharing of Chromatin Tracing datasets using the newly developed 4DN FISH Omics Format.

ArXiv·2025
Same author

Spatial multi-omics of nuclear architecture with two-layer seqFISH.

Nature reviews. Genetics·2025
Same author

Spatial multi-omics reveals cell-type-specific nuclear compartments.

Nature·2025
Same author

Genome organization around nuclear speckles drives mRNA splicing efficiency.

Nature·2024
Same journal

A native sulfur deposit in Gale crater, Mars.

Science (New York, N.Y.)·2026
Same journal

Coordinated demise of harmful algal blooms.

Science (New York, N.Y.)·2026
Same journal

Genetic effects put into context.

Science (New York, N.Y.)·2026
Same journal

Bacteria share proteins to survive antibiotics.

Science (New York, N.Y.)·2026
Same journal

Impacts shaped Earth's first continents.

Science (New York, N.Y.)·2026
Same journal

Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

Science (New York, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: May 7, 2026

Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

13.4K

Imaging nuclear architecture in single cells.

Yodai Takei1

  • 1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

Science (New York, N.Y.)
|November 16, 2023
PubMed
Summary
This summary is machine-generated.

Multiplexed imaging generates detailed 3D maps of individual cell nuclei. This advanced technique provides unprecedented spatial resolution for nuclear organization studies.

More Related Videos

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
09:56

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Published on: April 30, 2019

6.6K
Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy
08:49

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Published on: August 1, 2022

3.6K

Related Experiment Videos

Last Updated: May 7, 2026

Single-Molecule Imaging of Nuclear Transport
12:13

Single-Molecule Imaging of Nuclear Transport

Published on: June 9, 2010

13.4K
Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging
09:56

Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging

Published on: April 30, 2019

6.6K
Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy
08:49

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Published on: August 1, 2022

3.6K

Area of Science:

  • Cell biology
  • Molecular imaging
  • Genomics

Background:

  • Understanding nuclear organization is crucial for cellular function.
  • Current imaging techniques have limitations in 3D resolution and multiplexing.
  • Precise mapping of nuclear substructures is needed.

Purpose of the Study:

  • To develop and validate a novel multiplexed imaging approach.
  • To demonstrate the capability of creating high-resolution 3D maps of single nuclei.

Main Methods:

  • Utilized advanced multiplexed imaging techniques.
  • Developed computational methods for 3D reconstruction and analysis.
  • Applied the method to map key nuclear components.

Main Results:

  • Achieved precise three-dimensional spatial mapping of single nuclei.
  • Successfully visualized complex nuclear architectures with high fidelity.
  • Demonstrated multiplexing capability for simultaneous detection of multiple targets.

Conclusions:

  • Multiplexed imaging offers a powerful tool for nuclear architecture research.
  • This technique enables detailed 3D mapping of nuclear organization.
  • Opens new avenues for studying genome organization and function.