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Related Experiment Videos

PCP intoxication in seven young children.

R H Schwartz, A Einhorn

    Pediatric Emergency Care
    |December 1, 1986
    PubMed
    Summary

    Phencyclidine (PCP) intoxication in young children presents with neurological symptoms like unresponsiveness and ataxia, differing from adult presentations. Early urine toxicology screening is crucial for diagnosis in pediatric emergencies.

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    Area of Science:

    • Pediatric Emergency Medicine
    • Clinical Toxicology

    Background:

    • Phencyclidine (PCP) is a dissociative anesthetic with known psychoactive effects.
    • Intoxication in pediatric populations is less documented than in adults.

    Observation:

    • Five infants and two young children presented with PCP intoxication.
    • Neurological signs predominated, including diminished responsiveness, ataxia, nystagmus, and constricted pupils.
    • Behavioral symptoms like aggression, common in adults, were notably absent.

    Findings:

    • Pediatric PCP intoxication manifests primarily as neurological deficits rather than behavioral changes.
    • Parental denial of drug exposure was common.
    • PCP urine toxicology screening is recommended for pediatric emergencies with unexplained neurological symptoms.

    Implications:

    • Highlights the need for increased awareness of PCP intoxication in infants and young children.
    • Suggests specific clinical presentations warranting toxicology screening for PCP.
    • Informs diagnostic approaches in pediatric emergency settings for undiagnosed unresponsiveness or neurological abnormalities.

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