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Updated: Jul 11, 2025

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
Multiple enteric muco-submucosal elongated polyps causing intussusception.
Atsuki Taniguchi1, Izuru Endo2, Takeyoshi Nishiyama2
1Department of Surgery, Mitoyo General Hospital, 809, Toyohama-cho Himehama, Kanonji-shi, Kagawa, 769-1695, Japan. t.atsuki9896@gmail.com.
Multiple muco-submucosal elongated polyps (MSEP) caused intussusception in a young woman. This case highlights rare jejunal MSEP and their potential to induce intestinal obstruction.
Area of Science:
- Gastroenterology
- Pathology
- Surgical Oncology
Background:
- Intestinal polyps are growths in the gastrointestinal tract, varying in neoplastic potential.
- Muco-submucosal elongated polyps (MSEP) are typically non-neoplastic and historically reported in the colon.
- Small intestinal polyps, especially multiple lesions causing obstruction, are less commonly documented.
Observation:
- A 20-year-old female presented with abdominal pain and was diagnosed with multiple upper jejunal masses.
- Computed tomography identified masses suspected as lipomas, leading to surgical resection due to intussusception.
- Pathological analysis revealed the masses were muco-submucosal elongated polyps (MSEP), characterized by mucosal and edematous submucosal tissue with vascular and lymphatic dilation.
Findings:
- The jejunal masses were definitively diagnosed as multiple muco-submucosal elongated polyps (MSEP), a non-neoplastic entity.
- These MSEPs were identified as the cause of intussusception, leading to small bowel obstruction.
- The case represents a rare instance of multiple MSEPs occurring in the jejunum and inducing intussusception.
Implications:
- This case expands the known anatomical distribution of MSEP beyond the colon to the small intestine, specifically the jejunum.
- Understanding the pathogenesis of jejunal MSEP is crucial for accurate diagnosis and management of intussusception.
- Further research into similar cases can elucidate the mechanisms by which these polyps cause intestinal intussusception.
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