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Related Concept Videos

Dementia01:30

Dementia

117
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
117
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

496
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
496
Amnesia01:13

Amnesia

128
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
128
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

196
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
196
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

560
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
560
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

1.3K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
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Related Experiment Video

Updated: Jul 11, 2025

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

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Dementia: Dementia Types.

Jason Wilbur1

  • 1Carver College of Medicine at the University of Iowa, Iowa City, IA.

FP Essentials
|November 17, 2023
PubMed
Summary

Dementia, a progressive cognitive decline, has multiple causes including Alzheimer's and vascular dementia. Early detection through validated tools is crucial for management, despite no universal screening recommendations.

Area of Science:

  • Neurology
  • Geriatrics
  • Cognitive Science

Background:

  • Dementia, or major neurocognitive disorder, is a chronic, progressive loss of cognitive function.
  • It is a geriatric syndrome with various underlying causes, requiring careful diagnosis.
  • While universal screening for cognitive impairment lacks evidence, clinician vigilance for patient/caregiver concerns is vital.

Purpose of the Study:

  • To provide an overview of dementia and its common forms.
  • To highlight the importance of accurate diagnosis for treatment and prognosis.
  • To differentiate between major types of dementia.

Main Methods:

  • Review of existing literature on dementia and its subtypes.
  • Clinical presentation and diagnostic considerations for various dementias.

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Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
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  • Emphasis on validated cognitive assessment tools.

    • Main Results:

    • Alzheimer disease is the most common cause, characterized by insidious onset and progressive decline.
    • Vascular dementia is the second most common, often co-occurring with other cognitive disorders.
    • Lewy body dementias and frontotemporal dementias present distinct features regarding motor/cognitive symptom onset and progression.

    Conclusions:

    • Understanding the diverse causes of dementia aids accurate diagnosis and tailored treatment.
    • Differentiating dementia subtypes is essential for appropriate patient counseling and prognosis.
    • Clinician alertness to cognitive changes and use of assessment tools are key for early identification.