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Updated: Jul 11, 2025

05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
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Occult bowel cancer presenting as Morvan syndrome
Shyama Alagoda1, Sunil Wimalaratna2, Tharuka Milinda Herath3
1Clinical Neurophyisology, Somerset NHS Foundation Trust, Taunton, UK.
BMJ Case Reports
|November 17, 2023
Summary
A man with Morvan syndrome and underlying bowel cancer experienced symptom improvement after surgical tumor removal. Early cancer detection was crucial for curative treatment, though neurological symptoms persisted.
Area of Science:
- Neurology
- Oncology
- Immunology
Background:
- Morvan syndrome is a rare autoimmune disorder characterized by peripheral nerve hyperexcitability and central nervous system dysfunction.
- Contactin-associated protein-like 2 (CASPR2) antibodies are implicated in the pathogenesis of Morvan syndrome.
- Association between autoimmune disorders and occult malignancies necessitates thorough oncological screening.
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