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Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
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Corneal transplantation: A walk to vision
S K Mishra1, Amrita Joshi2, P M Ginu3
1Consultant & Head (Ophthalmology), Army Hospital (R & R), Delhi Cantt, India.
Medical Journal, Armed Forces India
|November 20, 2023
Summary
Corneal transplantation has evolved significantly over 100 years, improving treatments for corneal diseases and blindness. Advances in surgical techniques, from full transplants to lamellar keratoplasty, offer new hope.
Area of Science:
- Ophthalmology
- Regenerative Medicine
Background:
- Corneal diseases represent a significant global cause of vision impairment and blindness.
- Corneal transplantation is a critical intervention for advanced corneal pathologies.
Purpose of the Study:
- To review the historical evolution of corneal transplantation over the past century.
- To outline the indications, potential complications, and surgical techniques in corneal transplantation.
Main Methods:
- Literature review of historical and contemporary corneal transplantation practices.
- Analysis of surgical advancements from penetrating keratoplasty to lamellar keratoplasty.
Main Results:
- Corneal transplantation techniques have progressed substantially over 100 years.
- Innovations include the development of lamellar keratoplasty, offering alternatives to full-thickness transplants.
Conclusions:
- Significant technical advancements in corneal transplantation have driven progress in combating blindness.
- The evolution of these procedures continues to generate interest and momentum in ophthalmology.

