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[Infectious endocarditis: its resistance to therapy, causative factors and means of combating it]
Abstract:
Based on the data obtained during observation over 270 patients with infectious endocarditis the authors discuss factors that cause antibacterial therapy resistance encountered particularly often over the recent decade. Among the factors, the authors mark polyetiology of the disease over the recent years, "new" patterns of endocarditis in terms of the pathogenesis, predominance of primary endocarditis with highly virulent microorganisms, late disease diagnosis, inadequate antibacterial treatment, and so forth. Approaches to overcoming treatment resistance are also considered.
Insights
This study examines infectious endocarditis, identifying key factors contributing to rising antibacterial resistance. Strategies to overcome this resistance in infectious endocarditis treatment are also discussed.
Area of Science:
- Infectious Diseases
- Pharmacology
- Clinical Medicine
Background:
- Infectious endocarditis presents increasing challenges due to rising antibacterial resistance.
- Recent decades show a growing prevalence of difficult-to-treat endocarditis cases.