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The Thyroid Gland

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

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One nodule-one punction-one slide: Optimizing thyroid fine-needle aspiration for a digital workflow.

Ariana Maia¹, Bárbara Carvalho², João Vale^2,3

¹Endocrinology Department, Centro Hospitalar Universitário de Santo António, Porto, Portugal.

Cytopathology : Official Journal of the British Society for Clinical Cytology

|November 20, 2023

Summary

Optimizing thyroid fine-needle aspiration biopsy (FNAB) by using one slide instead of two significantly reduces diagnostic time and digital file size. This

Keywords:

digital pathology fine‐needle aspiration biopsy interventional pathologist thyroid

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Area of Science:

Pathology
Cytopathology
Medical Imaging

Background:

Interventional pathologists increasingly perform ultrasound-guided thyroid fine-needle aspiration biopsy (FNAB).
Optimization of FNAB procedures is crucial due to resource limitations and digital workflow integration.
Evaluating sample adequacy and diagnostic efficiency is essential for improving patient care.

Purpose of the Study:

To compare the adequacy of FNAB samples using one versus two slides for cytopathological analysis.
To assess the influence of slide number on diagnosis categorization, turnaround time, and digital workflow efficiency.
To determine the impact on scanning time and digital file size for thyroid nodule biopsies.

Main Methods:

Retrospective analysis of thyroid nodule FNAB cases, categorized into one-slide and two-slide groups.
Cytological diagnoses were made using the second edition of the Bethesda System for Reporting Thyroid Cytopathology.
Initial 15 cases from each group were selected for scanning and digital file analysis.

Main Results:

No significant differences in nodule size, location, or EU-TIRADS classification were observed between groups.
The one-slide group showed no increased prevalence of non-diagnostic or atypia of undetermined significance (AUS) categories.
The one-slide group achieved diagnoses 1.2 days faster, with significantly reduced scanning time and digital file size.

Conclusions:

The 'one nodule-one puncture-one slide' strategy optimizes thyroid FNAB procedures for digital workflows.
This approach enhances procedural efficiency and leads to cost savings.
Diagnostic accuracy is maintained, making it a viable strategy for thyroid nodule evaluation.