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Physical activity in liver transplant recipients: a large multicenter study
Stefano Gitto1, Lucia Golfieri2, Filippo Gabrielli3
1Internal Medicine and Liver Unit, University Hospital Careggi, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy. stefano.gitto@unifi.it.
Internal and Emergency Medicine
|November 20, 2023
Summary
Many liver transplant recipients have low physical activity levels, increasing over time post-transplant. Inactivity is linked to poor diet and quality of life, highlighting the need for lifestyle interventions.
Area of Science:
- Transplant Medicine
- Lifestyle Medicine
- Public Health
Background:
- Liver transplant (LT) recipients require a healthy lifestyle and appropriate diet for optimal outcomes.
- Understanding physical activity patterns is crucial for post-transplant care.
Purpose of the Study:
- To analyze physical activity patterns in liver transplant recipients.
- To identify factors associated with physical activity levels and inactivity.
Main Methods:
- A composite questionnaire assessed physical activity, Mediterranean Diet (MD) adherence, quality of life (QoL), and employment in 511 stable LT recipients.
- Statistical analyses included Pearson correlations, t-tests, ANOVAs, and multivariable logistic regression.
Main Results:
- 193 patients had high physical activity, 197 minimal, and 121 insufficient activity (29 totally inactive).
- Almost all active patients engaged in low-quality, non-structured activity.
- Inactivity was independently associated with time from LT, sedentary lifestyle, low MD adherence, and low QoL (physical dimension).
Conclusions:
- A significant proportion of liver transplant recipients exhibit insufficient or no physical activity.
- Physical inactivity increases with time post-LT and is strongly linked to suboptimal diet and reduced quality of life.
