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Effect of papillary muscle and trabeculae on left ventricular function analysis via computed tomography: A
Minji Kim1, Seulgi You, Taeyang Ha
1Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
Insights
Including or excluding papillary muscles and trabeculae in cardiac computed tomography (CT) significantly impacts left ventricular (LV) functional parameters and myocardial mass quantification. Consistent methodology is crucial for accurate diagnosis and therapy monitoring.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
- Cardiac Anatomy
Background:
- Quantification of left ventricular (LV) functional parameters and myocardial mass is critical for cardiovascular disease diagnosis and management.
- The inclusion or exclusion of papillary muscles and trabeculae in LV volume and mass calculations can significantly alter these measurements.
- Standardized imaging protocols are necessary to ensure consistent and reliable diagnostic assessments.
Purpose of the Study:
- To determine standard values for the proportion of papillary muscles and trabeculae in normal adults using cardiac computed tomography (CT).
- To investigate the impact of including or excluding papillary muscles and trabeculae on LV functional parameters across different patient groups.
- To provide guidance on consistent methodology for LV quantification in clinical practice.
Main Methods:
- Utilized cardiac computed tomography (CT) to acquire imaging data in a cohort of normal adult subjects.
- Quantified the percentage contribution of papillary muscles and trabeculae to LV end-diastolic volume (EDV) and LV mass (LVM).
- Analyzed the effect of papillary muscle and trabeculae inclusion/exclusion on LV functional parameters.
Main Results:
- Papillary muscles and trabeculae constituted 11.9 ± 5.6% of LV end-diastolic volume (EDV) and 20.2 ± 4.3% of LV mass (LVM).
- Exclusion of papillary muscles simplified automated contour detection in CT imaging.
- The inclusion or exclusion significantly affected disease diagnosis, highlighting the clinical relevance of this methodological choice.
Conclusions:
- The proportion of papillary muscles and trabeculae significantly impacts LV functional parameter and myocardial mass quantification.
- Consistent imaging protocols, either including or excluding these structures, are essential for accurate follow-up measurements.
- Standardizing the method of papillary muscle and trabeculae handling in CT analysis is crucial for reliable cardiovascular assessments.
Abstract:
Deciding whether to include or exclude the papillary muscles and trabeculae to blood pool is essential, because quantifications of left ventricular (LV) functional parameters and myocardial mass are significantly affected. As a result, such inclusion or exclusion might produce different indices for diagnosis and therapy. Using cardiac computed tomography (CT), we obtained standard values of the portion of papillary muscle and trabeculae in normal adults, and to find out how the inclusion or exclusion of papillary muscle and trabeculae affect LV functional parameters depending on the patient group. Excluding the papillary muscles from the LV mass results in easier automated contour detection using CT. The percentage portions of papillary muscle and trabeculae to LV end-diastolic volume (EDV) and LV mass (LVM) were 11.9 ± 5.6% and 20.2 ± 4.3%, respectively, significantly affecting disease diagnosis. Imaging should be consistent at follow-up and include or exclude the papillary muscles and trabeculae to avoid introducing significant differences between measurements.
