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Updated: Jul 10, 2025

Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Synthesis of core-shell polymer particles in supercritical carbon dioxide via iterative monomer addition
Kristoffer Kortsen1, Morgan Reynolds-Green1, Bradley Hopkins1,2
1School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK. steve.howdle@nottingham.ac.uk.
Abstract:
A new, robust methodology for the synthesis of polystyrene-poly(methyl methacrylate) (PS-PMMA) core-shell particles using seeded dispersion polymerisation in supercritical carbon dioxide is reported, where the core-shell ratio can be controlled predictably via manipulation of reagent stoichiometry. The key development is the application of an iterative addition of the MMA shell monomer to the pre-prepared PS core. Analysis of the materials with differing core-shell ratios indicates that all are isolated as single particle populations with distinct and controllable core-shell morphologies.
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