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Updated: Jul 10, 2025

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Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
Published on: October 4, 2019
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Polymer Implantable Electrode Foundry: A shared resource for manufacturing polymer-based microelectrodes for neural
Kee Scholten1, Huijing Xu1, Zhouxiao Lu1
1Alfred E. Mann Department of Biomedical Engineering, University of Southern California, Los Angeles, USA.
Biorxiv : the Preprint Server for Biology
|November 21, 2023
Summary
Researchers can now access advanced polymer microelectrode arrays for neural recording. The Polymer Implantable Electrode (PIE) Foundry increases accessibility for neuroscience research, improving long-term signal quality.
Area of Science:
- Neuroscience
- Biomaterials Engineering
- Implantable Devices
Background:
- Chronic electrophysiological recording is crucial for monitoring neural activity at the single unit level.
- Immunological responses to implanted electrodes often degrade signal quality over time.
- Soft, flexible polymer microelectrode arrays offer improved device-tissue integration and signal stability.
Conclusions:
- The PIE Foundry democratizes access to critical neurotechnology.
- Supports advancements in long-term neural monitoring and research.
- Enables more researchers to conduct high-resolution electrophysiology studies.

