Imaging in pediatric disorders of the gut-brain interactions: current best practice and future directions

Shaman Rajindrajith1,2, Wathsala Hathagoda1,2, Eranga Ganewatte2

  • 1Department of Paediatrics, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka.

Insights

Radiological investigations are crucial for evaluating pediatric Disorders of Gut-Brain Interactions (DGBI). Novel imaging techniques promise to revolutionize DGBI diagnosis and treatment, offering better insights into the gut-brain axis.

Area of Science:

  • Pediatric Gastroenterology
  • Neurogastroenterology
  • Medical Imaging

Background:

  • Disorders of Gut-Brain Interactions (DGBI) present common yet challenging clinical scenarios in pediatric patients.
  • Radiological investigations are frequently employed to assess children experiencing DGBI.

Purpose of the Study:

  • To review current best practices for radiological investigations in pediatric DGBI.
  • To explore the potential of novel radiological approaches to transform DGBI assessment and treatment in children.

Main Methods:

  • Review of current literature on radiological investigations for pediatric DGBI.
  • Discussion of emerging and novel imaging modalities.

Main Results:

  • Current imaging practices for DGBI are discussed.
  • Novel imaging techniques show potential for revolutionizing diagnosis and treatment.

Conclusions:

  • Pediatric DGBI imaging is evolving, with significant potential to transform diagnosis and therapy.
  • Advancements in understanding the gut-brain axis will drive the development of sophisticated, lower-radiation imaging techniques.
  • Novel modalities offer enhanced insights into the gut-brain axis, improving therapeutic options for children with DGBI.
Abstract

Related Concept Videos

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
87
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
234
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
252
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
123