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Updated: Jul 10, 2025

Preparation of Acute Human Hippocampal Slices for Electrophysiological Recordings
Published on: May 7, 2020
Interpretation of the Intracranial Electroencephalogram of the Human Hippocampus
1Comprehensive Epilepsy Center, Northwestern Memorial Hospital, 675 North Street Clair Street, Galter 7-109, Chicago, IL 60611, USA.
Abstract:
Understanding and discriminating the normal and abnormal elements of the intracranial electroencephalogram (iEEG) is essential in decision-making for epilepsy surgery. The hippocampus is widely acknowledged as a key structure in decision-making processes for surgical treatment in temporal lobe epilepsy and epilepsies that involve the mesial temporal structures. This review will provide a summary of the current state of our knowledge and understanding regarding normal and abnormal features of the iEEG of the human hippocampus.

