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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
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Endovascular Treatment of Type A Aortic Dissection: A Systematic Review and Meta-Analysis Using Reconstructed
Konstantinos S Mylonas1,2, Ioannis Zoupas2,3, Panagiotis T Tasoudis3
1Department of Cardiac Surgery, Onassis Cardiac Surgery Center, 176 74 Athens, Greece.
Journal of Clinical Medicine
|November 25, 2023
Summary
Thoracic endovascular aortic repair (TEVAR) is feasible for select patients with type A aortic dissections (TAAD) unsuitable for open surgery. Further research is needed to define its long-term role in TAAD treatment.
Area of Science:
- Cardiovascular Surgery
- Endovascular Interventions
- Aortic Disease Management
Background:
- Open surgery is the gold standard for type A aortic dissections (TAAD).
- Thoracic endovascular aortic repair (TEVAR) is considered for highly selected patients.
- This study evaluates TEVAR outcomes in TAAD patients unfit for open surgery.
Purpose of the Study:
- To assess the feasibility and outcomes of TEVAR in TAAD patients.
- To evaluate endovascular treatment for individuals unsuitable for open repair.
- To analyze survival and complication rates associated with TEVAR in this cohort.
Main Methods:
- PRISMA-compliant systematic review of PubMed, Scopus, and Cochrane databases.
- Inclusion of 20 eligible studies with 311 patients undergoing TEVAR for TAAD.
- Time-to-event data analyzed using Kaplan-Meier curves.
Main Results:
- Mean age was 60.7 years; 75.48% were male.
- Low rates of conversion to open surgery (0.44%), technical failure (0.22%), and stroke (0.1%).
- One-, three-, and five-year survival rates were 87.15%, 82.52%, and 82.31%, respectively.
Conclusions:
- TEVAR is a feasible option for carefully selected TAAD patients unable to undergo open surgery.
- Long-term data and overcoming technical challenges are crucial for defining TEVAR's role.
- Further investigation is warranted to establish endovascular treatment in TAAD repair.
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