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Updated: Jul 10, 2025

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Primary Care Patient Interest in Multi-Cancer Early Detection for Cancer Screening.

Ronald E Myers1, Mie H Hallman1, Ayako Shimada2

  • 1Division of Population Science, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Journal of Personalized Medicine
|November 25, 2023
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Most patients are interested in multi-cancer early detection (MCED) tests, especially if recommended and effective. Further research is needed to understand patient uptake in routine care settings.

Keywords:
cancer screeningmulti-cancer early detection testsprimary care

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Area of Science:

  • Oncology
  • Genomics
  • Preventive Medicine

Background:

  • Multi-cancer early detection (MCED) tests show promise for cancer screening.
  • Patient receptivity to MCED tests is largely unknown.
  • Understanding patient interest is crucial for clinical implementation.

Purpose of the Study:

  • To assess patient interest in emerging MCED blood tests.
  • To identify factors associated with patient interest in MCED testing.

Main Methods:

  • Prospective, observational study utilizing telephone surveys.
  • Surveyed primary care patients (n=159) in an urban health system.
  • Multivariable analyses identified factors influencing interest.

Main Results:

  • 79% of respondents expressed high interest in MCED testing.
  • Interest was not linked to personal characteristics.
  • Interest positively correlated with expectations of recommendation, convenience, and effectiveness (OR = 11.70).

Conclusions:

  • Significant patient interest exists for MCED tests.
  • Perceived effectiveness and recommendation are key drivers of interest.
  • Further studies should evaluate patient uptake in real-world clinical settings.