Related Experiment Video

Updated: Jul 10, 2025

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier
07:53

Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier

Published on: April 26, 2016

11.2K

Innovative Topical Patches for Non-Melanoma Skin Cancer: Current Challenges and Key Formulation Considerations

Sangseo Kim1, Candace M Day1, Yunmei Song1

  • 1Centre for Pharmaceutical Innovation, Clinical and Health Sciences, University of South Australia, Adelaide, SA 5000, Australia.

Pharmaceutics
|November 25, 2023
PubMed

Insights

Topical patches offer a promising solution for non-melanoma skin cancer (NMSC) treatment, improving drug delivery and patient adherence compared to conventional methods. This review details advancements in NMSC topical patch technology.

Area of Science:

  • Dermatology
  • Oncology
  • Materials Science

Background:

  • Non-melanoma skin cancer (NMSC) is the most common cancer globally, with millions of new cases annually.
  • Topical treatments are standard for early-stage NMSC but face challenges like poor drug penetration and patient compliance.
  • Advanced drug delivery systems, particularly topical patches, are being explored to enhance NMSC treatment efficacy.

Purpose of the Study:

  • To review current advancements in innovative topical patches for NMSC treatment.
  • To discuss the potential of topical patches in overcoming limitations of conventional NMSC therapies.
  • To provide insights into key considerations and emerging trends in NMSC topical patch development.

Main Methods:

  • Comprehensive literature review of NMSC topical treatments and advanced drug delivery systems.
  • Focus on innovative topical patch technologies for localized NMSC intervention.
  • Analysis of current research, key considerations, and future trends in patch development.

Main Results:

  • Topical patches show potential to improve drug penetration and patient adherence for NMSC treatment.
  • A wide range of innovative topical patch designs and materials are emerging for NMSC therapy.
  • This review synthesizes current advancements, offering a consolidated view of the field.

Conclusions:

  • Advanced topical patches represent a significant innovation in localized NMSC treatment.
  • Further research and clinical trials are encouraged to explore the full potential of these systems.
  • Topical patches may offer a more effective and patient-friendly approach to managing NMSC.
Keywords:
drug deliveryformulationmicroneedlesnanotechnologynon-melanoma skin cancertopical patches

More Related Videos

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression11:02

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression

Published on: August 3, 2011

49.7K
Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging11:07

Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging

Published on: November 24, 2021

2.8K

Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.2K
Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
376
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.5K
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.6K
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
529