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Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
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The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
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Immune-Cell-Based Therapy for COVID-19: Current Status.

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Cell therapy shows promise for treating COVID-19 by modulating immune responses. This review covers immune cells in COVID-19 pathogenesis and current cell therapy strategies.

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Area of Science:

  • Immunology
  • Infectious Diseases
  • Cell Therapy

Background:

  • COVID-19, caused by SARS-CoV-2, is a global pandemic.
  • Immune responses are critical in managing COVID-19.
  • Cell therapy is a novel approach to immune modulation.

Purpose of the Study:

  • To review immune cell subsets involved in COVID-19 pathogenesis.
  • To summarize the current status of cell therapy for COVID-19.

Main Methods:

  • Literature review of immune cell subsets in COVID-19.
  • Analysis of current cell therapy research and clinical trials for COVID-19.

Main Results:

  • Identified key immune cell subsets contributing to COVID-19.
  • Detailed the landscape of ongoing cell therapy research for COVID-19.

Conclusions:

  • Cell therapy offers a customizable and regenerative approach to COVID-19 treatment.
  • Further research is needed to optimize cell therapy strategies for COVID-19.