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Updated: Jul 10, 2025

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Published on: March 28, 2025
[Ascending aortic disease: is general perception updated to current guidelines?]
Pasquale Totaro1, Antonio Sciortino1, Filippo Amoroso1
1U.O.C. Cardiochirurgia, IRCCS Fondazione Policlinico San Matteo, Pavia.
Insights
Many patients with thoracic aorta diseases are referred urgently despite moderate dilation, indicating suboptimal clinical awareness. Improved physician education is crucial to better identify and manage serious aortic conditions, reducing acute aortic syndrome risks.
Area of Science:
- Cardiology
- Vascular Surgery
- Public Health
Background:
Thoracic aorta diseases represent a frequent cause of hospitalization and up to 15% of workload of a modern cardiac surgery centre. A dedicated thoracic aorta disease clinic was launched at our Division in January 2020. The clinic was open for new referrals as well as for preoperative and postoperative follow-up of patients. Here we report a summary of the activity of such dedicated clinic correlated to current international guidelines.
Methods:
Overall, 288 patients were seen at the clinic: 84 (29%) new referrals; 28 (10%) for preoperative follow-up and 176 (61%) for postoperative follow-up. New referrals included urgent referral (n = 57, 68%) and scheduled referral (n = 27, 32%). The majority of urgent new referrals were from general practitioners (n = 34, 60%). Postoperative follow-up also included a minority (n = 27, 15%) of urgent referrals.
Results:
Within new referrals, according to current guidelines, only 7% (n = 6) had surgical indication at time of referral (40% of urgent referral); 34% (n = 28) were in the so-called grey zone and required close follow-up (26% of urgent referrals); 59% (n = 50) had no significant aortic disease to require neither urgent specialist consultation nor close follow-up (85% of urgent referrals). Within postoperative follow-up, 7% (n = 12) required surgical reintervention (none with urgent referral). Furthermore, the majority of new referrals (especially within urgent referrals) showed only moderate aortic dilation.
Conclusions:
Current perception of clinical severity of thoracic aorta diseases is still suboptimal. Most patients are indeed referred as urgent despite non-significant aortic dilation. In contrast, potentially dangerous situations are frequently underestimated. An accurate territorial policy of sensitization and updating focused on thoracic aorta diseases is therefore essential in order to reduce the risks of acute aortic syndromes in our country.
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