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Updated: Jul 9, 2025

Preparation of Bead-supported Lipid Bilayers to Study the Particulate Output of T Cell Immune Synapses
Published on: April 1, 2022
Lipid metabolism in B cell biology
Rens Peeters1,2, Julia Jellusova1,2
1School of Medicine and Health, Institute of Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Germany.
None:
In recent years, the field of immunometabolism has solidified its position as a prominent area of investigation within the realm of immunological research. An expanding body of scientific literature has unveiled the intricate interplay between energy homeostasis, signalling molecules, and metabolites in relation to fundamental aspects of our immune cells. It is now widely accepted that disruptions in metabolic equilibrium can give rise to a myriad of pathological conditions, ranging from autoimmune disorders to cancer. Emerging evidence, although sometimes fragmented and anecdotal, has highlighted the indispensable role of lipids in modulating the behaviour of immune cells, including B cells. In light of these findings, this review aims to provide a comprehensive overview of the current state of knowledge regarding lipid metabolism in the context of B cell biology.
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