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Related Concept Videos

Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Jul 9, 2025

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
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Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

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Lung functional imaging.

Sam Bayat1,2, Jim Wild3,4, Tilo Winkler5

  • 1Department of Pulmonology and Physiology, CHU Grenoble Alpes, Grenoble, France.

Breathe (Sheffield, England)
|November 29, 2023
PubMed
Summary
This summary is machine-generated.

Pulmonary functional imaging offers quantitative insights into lung health, assessing ventilation, perfusion, and biomechanics. This review details methods and their utility in diagnosing and understanding respiratory diseases.

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Area of Science:

  • Pulmonary Medicine
  • Radiology
  • Medical Imaging

Background:

  • Pulmonary functional imaging provides quantitative assessment of regional lung function.
  • Modalities like CT, MRI, and nuclear imaging evaluate ventilation, perfusion, and biomechanics.
  • Understanding these parameters is crucial for diagnosing and managing respiratory disorders.

Purpose of the Study:

  • To review the rationale, strengths, and limitations of various lung functional imaging modalities.
  • To explain commonly measured regional lung function parameters.
  • To summarize the role of lung functional imaging in respiratory disease research and clinical practice.

Main Methods:

  • Review of established pulmonary functional imaging techniques including computed tomography (CT), magnetic resonance imaging (MRI), and nuclear imaging.
  • Analysis of key functional parameters such as ventilation, perfusion, microvascular gas exchange, and biomechanical properties.
  • Synthesis of evidence regarding the application of these techniques in major respiratory disorders.

Main Results:

  • Different imaging modalities offer unique insights into specific aspects of lung function.
  • Quantitative parameters provide objective measures for disease characterization and monitoring.
  • Lung functional imaging plays a vital role in early diagnosis, phenotyping, and understanding disease mechanisms.

Conclusions:

  • Pulmonary functional imaging is indispensable for comprehensive lung assessment.
  • It enhances diagnostic accuracy, disease phenotyping, and mechanistic understanding in respiratory medicine.
  • Continued development and application of these techniques will advance patient care for lung diseases.