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Pleural Effusion I: Introduction

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...

Pleural Effusion II: Symptoms and Management

Pleural Effusion II: Symptoms and Management

Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal Perforation-II: Clinical Manifestations and Management

Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:

Pneumothorax-II

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:

Pneumothorax-I

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

Pleural Disorders: Types and Brief Description

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:

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Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion

Published on: November 10, 2023

Etoricoxib-induced pleural effusion: A case report.

Bishal Kumar Sah¹, Ravi Ranjan Pradhan², Sangam Shah³

¹Institute of Medicine Tribhuvan University Maharajgunj Nepal.

Clinical Case Reports

|November 29, 2023

Summary

Drug-induced pleural effusion is a rare condition. This case highlights etoricoxib, a nonsteroidal anti-inflammatory drug, as a potential cause, emphasizing diagnosis by exclusion.

Keywords:

Nepal etoricoxib pleural effusion

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Area of Science:

Pharmacology
Pulmonology
Internal Medicine

Background:

Drug-induced pleural effusion is a rare clinical diagnosis.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed for pain and inflammation.
Etoricoxib, a selective COX-2 inhibitor, is known for fewer gastrointestinal side effects compared to traditional NSAIDs.

Observation:

A case report of a 45-year-old female patient is presented.
The patient developed pleural effusion.
The effusion was suspected to be induced by etoricoxib use.

Findings:

Pleural effusion associated with etoricoxib is an extremely rare side effect.
The diagnosis of drug-induced pleural effusion is one of exclusion.
Symptoms resolved upon discontinuation of the suspected causative drug.

Implications:

This case underscores the importance of considering drug-induced causes in unexplained pleural effusions.
Clinicians should maintain a high index of suspicion for rare adverse drug reactions, even with commonly prescribed medications.
Further investigation into the mechanisms of NSAID-induced pleural effusions may be warranted.