Challenges in catalyzing and sustaining research in translational science

Area of Science:

• * Translational Science
• * Clinical and Translational Science Awards (CTSA) Program
• * National Center for Advancing Translational Science (NCATS)

Background:

• * Defining translational science (TS) as distinct from translational research (TR) presents conceptual challenges.
• * Developing real-world investigations within the emerging field of TS requires innovative approaches.
• * The Clinical and Translational Science Awards (CTSA) Program prioritizes advancing TS and overcoming roadblocks.

Purpose of the Study:

• * To share obstacles encountered by the Einstein-Montefiore CTSA hub in generating institutional interest and research in TS.
• * To present potential strategies for addressing these identified challenges in translational science.
• * To stimulate broader dialogue within the CTSA community regarding the systematic pursuit of TS.

Main Methods:

• * Case study analysis of challenges faced by a specific CTSA hub (Einstein-Montefiore).
• * Identification and documentation of institutional barriers to TS research.
• * Development and proposal of strategic interventions to foster TS engagement.

Main Results:

• * Identified specific institutional hurdles in establishing TS as a distinct field of inquiry.
• * Proposed actionable strategies to overcome these barriers and promote TS research.
• * Highlighted the need for systematic examination of the 'science of translational science'.

Conclusions:

• * Collective sharing of experiences from CTSA hubs is critical for the growth of translational science.
• * Overcoming TS challenges requires innovative approaches and community-wide dialogue.
• * Enhanced recognition and acceptance of TS by scientific and broader communities are essential.