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Updated: Jul 9, 2025

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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
18.9K
Central effects of trigeminal electrical stimulation
Annalisa Monaco1, Ruggero Cattaneo1, Sara Di Nicolantonio1
1MeSVA Department, Dental Unit, University of L'Aquila, L'Aquila, Italy.
Cranio : the Journal of Craniomandibular Practice
|November 30, 2023
Summary
This review explores using sensory threshold ultra-low frequency transcutaneous electrical nerve stimulation (ULFTENS) in neuromodulation therapies. It highlights ULFTENS
Area of Science:
- Neuromodulation
- Neuroscience
- Pain Management
Background:
- Electro neuromodulation is a recognized therapy for cognitive and emotional disorders.
- Transcutaneous trigeminal stimulation is effective for orofacial pain.
- Current methods involve supraorbital, tongue, and tragus stimulation.
Purpose of the Study:
- To review neuromodulation techniques.
- To explore integrating sensory threshold ultra-low frequency transcutaneous electrical nerve stimulation (ULFTENS) into existing therapies.
- To investigate ULFTENS as an adjunct for temporomandibular disorders (TMD).
Main Methods:
- Literature review of neuromodulation techniques.
- Analysis of transcutaneous trigeminal stimulation protocols.
- Evaluation of sensory threshold ULFTENS application.
Main Results:
- Sensory threshold ULFTENS can be integrated into neuromodulation.
- ULFTENS may offer autonomic nervous system effects at sub-motor contraction levels.
- This approach is easy to implement with minimal side effects.
Conclusions:
- ULFTENS presents a novel approach for trigeminal neurostimulation.
- Dental ULFTENS can be a valuable addition to TMD treatment strategies.
- Low-level ULFTENS shows promise for therapeutic autonomic effects.

