Related Experiment Video
Updated: Jul 9, 2025

08:46
Implantation of Electrospun Vascular Grafts with Optimized Structure in a Rat Model
Published on: June 27, 2018
8.0K
Estimated diameter increase from a 4S to a 6S hamstring graft configuration - A cadaveric study
Yoan Bourgeault-Gagnon1, Alexandre Keith Leang2, Sonia Bédard3
1Sherbrooke University, 3001 12th Avenue North, Sherbooke, QC J1H 5H4, Canada.
SICOT-J
|November 30, 2023
Summary
The 6-strand hamstring autograft configuration significantly increases graft diameter by 1.5 mm compared to the 4-strand method. This 6-strand technique reliably achieves larger graft diameters for anterior cruciate ligament reconstruction.
Area of Science:
- Orthopedic surgery
- Biomechanical engineering
- Sports medicine
Background:
- Graft diameter is crucial for anterior cruciate ligament (ACL) reconstruction outcomes.
- Optimizing graft diameter can reduce the risk of ACL graft failure.
- Hamstring autografts are commonly used in ACL reconstruction.
Purpose of the Study:
- To evaluate the impact of a 6-strand (6S) hamstring autograft configuration on graft diameter.
- To compare the graft diameter of the 6S configuration against the standard 4-strand (4S) configuration.
Main Methods:
- A cadaveric study involving 33 knees.
- Hamstring tendons (semitendinosus and gracilis) were harvested.
- Graft diameter was measured for both 4S and 6S configurations by three evaluators.
Main Results:
- The 6S configuration resulted in a median diameter increase of 1.5 mm compared to the 4S configuration (p < 0.001).
- 84% of 6S grafts achieved a diameter > 8 mm, versus less than one-third of 4S grafts.
- The 6S configuration offers a reliable method to achieve larger graft diameters.
Conclusions:
- The 6S hamstring graft configuration significantly increases graft diameter compared to the 4S configuration.
- This technique is valuable for achieving target graft diameters (e.g., 8.5 mm) in ACL reconstruction.
- The findings aid in pre-operative and intra-operative decision-making for optimizing graft selection and surgical outcomes.

