Standardized 2D atrial mapping and its clinical applications.

Area of Science:

• Cardiology
• Medical Imaging
• Computational Anatomy

Background:

• Standardized 2D atrial mapping is needed for comparing patient electrophysiology.
• Complex atrial anatomy makes 3D to 2D geometry conversion challenging.

Purpose of the Study:

• To develop a standardized 2D atrial map connecting left and right atria.
• To maintain fixed segment positions and sizes across individuals for consistent analysis.

Main Methods:

• Atrial segmentation into 19 distinct regions (12 left, 5 right, 2 septum).
• Automated procedure to unfold atrial surfaces and project 3D data into 2D.
• Application of the 2D map for visualizing electrophysiological data like activation times and phase maps.

Main Results:

• Demonstrated visualization of electrophysiological properties in healthy and atrial fibrillation subjects.
• Enabled easy intra-subject interpretation and inter-subject comparison of atrial data.
• Provided a framework for analyzing atrial fibrillation substrate before and during catheter ablation.

Conclusions:

• The proposed standardized 2D atrial maps facilitate visualization and comparison of electrophysiological and structural data.
• This method aids in guiding catheter ablation and understanding atrial fibrillation mechanisms.
• Offers a consistent reference for analyzing atrial fibrillation substrate.