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High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
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Conduction velocity mapping in atrial fibrillation using omnipolar technology
Yousaku Okubo1, Naoto Oguri1, Takumi Sakai1
1Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Pacing and Clinical Electrophysiology : PACE
|December 2, 2023
Summary
Atrial slow conduction velocity (CV) areas are linked to atrial fibrillation (AF) recurrence after pulmonary vein isolation. Specifically, slow CV areas in the left atrial anterior region predict AF recurrence.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Atrial slow conduction velocity (CV) is implicated in atrial fibrillation (AF) perpetuation.
- Standardized criteria for CV measurement are lacking.
- Omnipolar technology (OT) offers novel methods for CV assessment.
Purpose of the Study:
- To investigate the relationship between slow CV area (SCVA) measured by OT and AF recurrence.
- To determine if SCVA is a predictor of AF recurrence post-pulmonary vein isolation (PVI).
Main Methods:
- Ninety AF patients undergoing PVI were studied.
- Left atrial (LA) electrophysiological mapping using OT measured SCVA pre-PVI.
- Proportion of SCVA at various CV cutoffs (<0.6 to <0.9 m/s) compared between AF recurrence groups.
Main Results:
- AF recurrence occurred in 25.5% of patients after a mean follow-up of 516 days.
- Higher SCVA proportions in the LA posterior, LA appendage (LAA), and LA anterior were observed in patients with AF recurrence.
- Multivariate analysis identified low voltage area and SCVA in the LA anterior (CV <0.7 m/s) as independent predictors of AF recurrence.
Conclusions:
- Evaluating local CV using OT is crucial.
- SCVA with CV <0.7 m/s in the LA anterior is strongly associated with AF recurrence after PVI.
